Our 650nm lasers units are ischemic diseases laser treatment devices that apply advanced techniques considering the actual pathologies of blood flow in the soft tissue. Application of the high-power lasers onto important acupunctural bases such as P6 or Hegu and LI4 or Neiguan significantly increase blood vessels dilatation through the production of nitric oxide (NO) a powerful vasodilator, leads to a relaxing of the vessels, increase blood circulation, reduction of vascular tone, hypertension, and a lot of oxygen to the tissues. This contributes most importantly in controlling coronary and peripheral artery diseases. Clinical evidence confirms consistent application of the devices improves microcirculation parameters of up to 15-20% within just 8 weeks. Non-invasive procedures also involves light aerobic exercises such as swimming and walking alongside the devices which greatly increase the effectiveness of these exercises aimed at the optimal enhancement of the blood flow and the cardiovascular condition.